雷帕霉素 | 53123-88-9

中文名雷帕霉素

中文同义雷帕霉素D3;雷帕霉素(98%细胞干扰/99%器官移植);雷帕霉素-D3 (雷帕霉素-D3);雷帕霉素/西罗莫司;雷帕酶素;雷帕霉素,来源于吸水链霉菌;MTOR抑制剂(RAPAMYCIN);依维莫司杂质17;西罗莫司

英文名Rapamycin

英文同义AY 22989;23,27-EPOXY-3H-PYRIDO(2,1-C)(1,4)OXAAZACYCLOHENTRIACONTINE;NSC-226080;RAPA;RAPAMUNE;RAPAMYCIN;RAPAMYCIN, STREPTOMYCES HYGROSCOPICUS;RPM

CAS53123-88-9

分子式C51H79NO13

分子量914.17

EINECS610-965-5

结构式

性质

熔点183-185°C

比旋光度D25 -58.2° (methanol)

沸点799.83°C (rough estimate)

密度1.0352 (rough estimate)

蒸气压0.56 hPa ( 20 °C)

折射率1.5280 (estimate)

闪点87 °C

储存条件-20°C

溶解度ethanol: soluble2MM

酸度系数(pKa)10.40±0.70(Predicted)

形态solution

颜色colorless to yellow

水溶解性Soluble in DMSO at 50mg/ml or methanol at 25mg/mlSoluble in alcohol, dimethyl sulfoxide and dimethyl formamide. Insoluble in water.

敏感性Moisture Sensitive/Light Sensitive/Hygroscopic

Merck14,8114